Application No: 2016-310Chief Investigator: Dr K Lycett
A life course approach to understanding how the first decade of life predicts cardiometabolic profiles at early adolescence: a longitudinal population-based study
Obesity affects one in four children and is strongly implicated in adult €diseases of ageing€, especially heart disease and diabetes. Typically, the implications of obesity have been examined in adulthood. Using novel data, we have a unique opportunity to explore which early growth patterns in the first decade (measured biennially) are most damaging to adolescent cardiometabolic health (lipid/inflammation). Ultimately, we hope that better prediction will avoid unnecessary intervention, while targeting research and treatment to those children with most to gain.